Do you have treatment-resistant depression (TRD)? A clinical research study is now enrolling eligible adults. The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an investigational medication in people with TRD.

You may be eligible to participate if you:

• Are 18 years of age or older
• Have been diagnosed with major depressive disorder (MDD)
• Have not responded to at least 2 different anti-depressant treatments

If interested, additional eligibility criteria will be assessed by the study doctor or staff. The commitment for the study is about 24 weeks.

Qualified patients may receive investigational study drug and some study-required medical care at no cost.