Immunovant/IMVT-1402-2502 This
study is testing IMVT-1402 vs Placebo in patients with Graves disease. Inclusion:
- 18-75 years old
- Diagnosed Graves Disease
- TSH <0.1
- TRAB ≥4.5
- On anti-thyroid drug for
≥ 3 months if treated with ≥20mg/day methimazole or equivalent
OR
- On anti-thyroid drug for
≥6 months of ≥10mg methimazole or equivalent
The study includes the following periods:
- Screening Period: up to
5 weeks
- Period 1 (blinded
treatment): 26 weeks
- Period 2 (blinded
treatment): 26 week
- Period 3 (off treatment
observation): 52 week
- Safety Follow-up Period:
approximately 4 weeks
The total duration of study participation is expected to be
up to 109 weeks for an individual participant.
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