Research Studies » Graves Disease

Immunovant/IMVT-1402-2502 This study is testing IMVT-1402 vs Placebo in patients with Graves disease.

Inclusion:

  • 18-75 years old
  • Diagnosed Graves Disease
  • TSH <0.1
  • TRAB ≥4.5
  • On anti-thyroid drug for ≥ 3 months if treated with ≥20mg/day methimazole or equivalent

OR

  • On anti-thyroid drug for ≥6 months of ≥10mg methimazole or equivalent

The study includes the following periods:

  • Screening Period: up to 5 weeks
  • Period 1 (blinded treatment): 26 weeks
  • Period 2 (blinded treatment): 26 week
  • Period 3 (off treatment observation): 52 week
  • Safety Follow-up Period: approximately 4 weeks

The total duration of study participation is expected to be up to 109 weeks for an individual participant.

 

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