Research Studies » Endometrial Hyperplasia

Endometrial hyperplasia is more likely to occur in women with the following risk factors:

Age older than 35 years
White race
Never having been pregnant
Older age at menopause
Early age when menstruation started
Personal history of certain conditions, such as diabetes mellitus , polycystic ovary syndrome, gallbladder disease, or thyroid disease

Cigarette smoking
Family history of ovarian, colon, or uterine cancer
What are the types of endometrial hyperplasia?
Endometrial hyperplasia is classified as simple or complex. It also is classified by whether certain cell changes are present
or absent. If abnormal changes are present, it is called atypical. The terms are combined to describe the exact kind of
Simple hyperplasia
Complex hyperplasia
Simple atypical hyperplasia
Complex atypical hyperplasia

What are signs and symptoms of endometrial hyperplasia?
The most common sign of hyperplasia is abnormal uterine bleeding. If you have any of the following, you should see your
health care provider:

Bleeding during the menstrual period that is heavier or lasts longer than usual
Menstrual cycles that are shorter than 21 days (counting from the first day of the menstrual period to the first day of the ext menstrual period)

Any bleeding after menopause
How is endometrial hyperplasia diagnosed?
There are many causes of abnormal uterine bleeding. If you have abnormal bleeding and you are 35 years or older, or if you
are younger than 35 years and your abnormal bleeding has not been helped by medication, your health care provider may
perform diagnostic tests for endometrial hyperplasia and cancer.
Transvaginal ultrasound
may be done to measure the thickness of the endometrium. For this test, a small device is
placed in your vagina. Sound waves from the device are converted into images of the pelvic organs. If the endometrium is
thick, it may mean that endometrial hyperplasia is present.
The only way to tell for certain that cancer is present is to take a small sample of tissue from the endometrium and study
it under a microscope. This can be done with an
endometrial biopsy,
dilation and curettage,

Reference: American College of Obstetricians and Gynecologists

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